{"id":341817,"date":"2024-10-19T23:58:26","date_gmt":"2024-10-19T23:58:26","guid":{"rendered":"https:\/\/pdfstandards.shop\/product\/uncategorized\/bs-en-128682017-tc\/"},"modified":"2024-10-25T23:11:46","modified_gmt":"2024-10-25T23:11:46","slug":"bs-en-128682017-tc","status":"publish","type":"product","link":"https:\/\/pdfstandards.shop\/product\/publishers\/bsi\/bs-en-128682017-tc\/","title":{"rendered":"BS EN 12868:2017 – TC"},"content":{"rendered":"
Tests have shown quite different results for Nitrosatables and that the tests are not reliable. The objective of the work will be to find a better way to determine Nitrosatables<\/p>\n
PDF Pages<\/th>\n | PDF Title<\/th>\n<\/tr>\n | ||||||
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1<\/td>\n | compares BS EN 12868:2017 <\/td>\n<\/tr>\n | ||||||
2<\/td>\n | TRACKED CHANGES Text example 1 \u2014 indicates added text (in green) <\/td>\n<\/tr>\n | ||||||
66<\/td>\n | 1 Scope 2 Normative references 3 Terms and definitions <\/td>\n<\/tr>\n | ||||||
67<\/td>\n | 4 Principle 5 Reagents <\/td>\n<\/tr>\n | ||||||
68<\/td>\n | 6 Apparatus <\/td>\n<\/tr>\n | ||||||
70<\/td>\n | 7 Standard Solutions of N-nitrosamines 7.1 General 7.2 N-nitrosamines identified in teats <\/td>\n<\/tr>\n | ||||||
71<\/td>\n | 7.3 Calibration solutions (for detector response) 7.4 N-nitrosamine used as internal standard 8 Procedure 8.1 General <\/td>\n<\/tr>\n | ||||||
72<\/td>\n | 8.2 Sample Preparation <\/td>\n<\/tr>\n | ||||||
73<\/td>\n | 8.3 Sample A (for determination of N-nitrosatable substances) 8.3.1 Preparation and pre-boiling 8.3.2 Preparation of Migrate A (for determining N-nitrosatable substances) See A.2 <\/td>\n<\/tr>\n | ||||||
74<\/td>\n | 8.3.3 Nitrosation of Migrate A (see A.3) and preparation of Solution A 8.4 Sample B (for determination of N-nitrosamines) 8.4.1 Preparation and pre-boiling 8.4.2 Preparation of Migrate B (for determining N-nitrosamines) 8.4.3 Preparation of Solution B 8.5 Preparation of extraction columns for Solutions A and B <\/td>\n<\/tr>\n | ||||||
75<\/td>\n | 8.6 Extraction of N-nitrosamines 8.6.1 From Solution A 8.6.2 From Solution B 8.7 Concentration of N-nitrosamines 8.7.1 In Extract A 8.7.1.1 General Procedure <\/td>\n<\/tr>\n | ||||||
76<\/td>\n | 8.7.1.2 Example 8.7.2 In Extract B 8.8 Blank Test 8.9 Analysis 8.9.1 Calibration function <\/td>\n<\/tr>\n | ||||||
77<\/td>\n | 8.9.2 Determination of sample concentration 9 Calculation of results 9.1 General <\/td>\n<\/tr>\n | ||||||
78<\/td>\n | 9.2 Variability of results and calculation of means 9.2.1 Requirements for variability 9.2.2 Test for variability 9.2.3 Calculation of means <\/td>\n<\/tr>\n | ||||||
79<\/td>\n | 9.3 Amount of total N-nitrosatable substances migrating from Sample A, analysed and expressed as N-nitrosamines from Concentrate A 9.4 Amount of total N-nitrosamines migrating from Sample B, analysed and expressed as N-nitrosamines from Concentrate B 10 Confirmation of N-nitrosamines <\/td>\n<\/tr>\n | ||||||
80<\/td>\n | 11 Analytical tolerances 11.1 General 11.2 Analytical tolerances (see Annex\u00a0F) 12 Compliance 13 Test report <\/td>\n<\/tr>\n | ||||||
82<\/td>\n | Annex\u00a0A (informative)Rationales A.1 General A.2 Migration Conditions (see 8.3.2) A.3 Nitrosation conditions (see 8.3.3) A.4 Weight of sample used (see 8.3.1) <\/td>\n<\/tr>\n | ||||||
83<\/td>\n | A.5 Separate migrations (see 8.3.2 and 8.3.3) A.6 Duplicate tests (see 8.1) A.7 TEA and alternative detectors <\/td>\n<\/tr>\n | ||||||
84<\/td>\n | A.8 Deviations (see 9.2, 9.3 and 11) A.9 Main differences between this standard and EN\u00a07112 [3] <\/td>\n<\/tr>\n | ||||||
85<\/td>\n | Annex\u00a0B (informative)Suitable gas chromatographic method <\/td>\n<\/tr>\n | ||||||
87<\/td>\n | Annex\u00a0C (normative)Example of results calculation and test report C.1 General C.2 Example for variability testing and means calculation for analytical results <\/td>\n<\/tr>\n | ||||||
89<\/td>\n | C.3 Results calculation and results table for test report <\/td>\n<\/tr>\n | ||||||
90<\/td>\n | C.4 Other Information for test report <\/td>\n<\/tr>\n | ||||||
91<\/td>\n | Annex\u00a0D (informative)Alternative Methods D.1 General D.2 Liquid Chromatography (LC) <\/td>\n<\/tr>\n | ||||||
92<\/td>\n | D.3 MS\/MS conditions <\/td>\n<\/tr>\n | ||||||
93<\/td>\n | D.4 Confirmation and quantification of detected N-nitrosamines <\/td>\n<\/tr>\n | ||||||
95<\/td>\n | Annex\u00a0E (informative)Justification of an N-nitrosamine specific adjustment for NDiNA <\/td>\n<\/tr>\n | ||||||
97<\/td>\n | Annex\u00a0F (informative)Summary of the 2015 validation trial F.1 Outline F.2 Initial statistical analysis \u2013 N-nitrosatable substances <\/td>\n<\/tr>\n | ||||||
98<\/td>\n | F.3 Reproducibility Limit for N-nitrosatable substances <\/td>\n<\/tr>\n | ||||||
99<\/td>\n | F.4 Consideration of the NDiNA Reproducibility limit F.5 Initial statistical analysis \u2013 N-nitrosamines <\/td>\n<\/tr>\n | ||||||
100<\/td>\n | F.6 Variability between Determinations <\/td>\n<\/tr>\n | ||||||
101<\/td>\n | F.7 Summary of Conclusions and implications for EN\u00a012868 <\/td>\n<\/tr>\n<\/table>\n","protected":false},"excerpt":{"rendered":" Tracked Changes. Child use and care articles. Method for determining the release of N-nitrosamines and N-nitrosatable substances from elastomer or rubber teats and soothers<\/b><\/p>\n |