ISO 23921:2020
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Cigarettes — Determination of tobacco specific nitrosamines in mainstream cigarette smoke with an intense smoking regime — Method using LC-MS/MS
| Published By | Publication Date | Number of Pages |
| ISO | 2020-09 | 22 |
This document specifies a method for the quantification of four tobacco specific nitrosamines (TSNAs) in the total particulate matter of cigarette mainstream smoke with the intense smoking regime specified in ISO 20778 by using reversed phase high performance liquid chromatography with tandem mass spectrometry (LC-MS/MS). The quantified TSNAs are: N-nitrosonornicotine (NNN), N-nitrosoanatabine (NAT), N-nitrosoanabasine (NAB) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).
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