ISO 17924:2018

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Soil quality — Assessment of human exposure from ingestion of soil and soil material — Procedure for the estimation of the human bioaccessibility/bioavailability of metals in soil

Published By	Publication Date	Number of Pages
ISO	2018-10	28

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Categories: 13.080.30 - Biological properties of soils, ISO

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Description

This document deals with the assessment of human exposure from ingestion of soil and soil materials. It specifies a physiologically based test procedure for the estimation of the human bioaccessibility of metals from contaminated soil in connection with the evaluation of the exposure related to human oral uptake.

The method is a sequential extraction using synthetic gastrointestinal fluids and can be used to estimate oral bioaccessibility. Soils or other geological materials, in sieved form, are extracted in an environment that simulates the basic physicochemical conditions of the human gastrointestinal tract.

This document describes a method to simulate the release of metals from soil and soil materials after passage through three compartments of the human gastrointestinal tract (mouth, stomach and small intestine). It produces extracts that are representative of the concentration of potentially harmful elements in the human gastrointestinal tract for subsequent chemical characterization.

NOTE 1 Bioaccessibility can be used to approximate oral bioavailability.

NOTE 2 The test has been validated for arsenic, cadmium and lead in an interlaboratory trial. The method has been in vivo validated to assess the oral bioavailability of arsenic, cadmium and lead.

Additional information

Published Code	ISO
Published By	International Organization for Standardization
Publication Date	2018-10
Pages Count	28
Language	English
Edition	1
File Size	706.6 KB
ICS Codes	13.080.30 - Biological properties of soils

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ISO 17924:2018

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