ASTM-E2045 2009
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E2045-99(2009) Standard Practice for Detailed Clinical Observations of Test Animals
Published By | Publication Date | Number of Pages |
ASTM | 2009 | 9 |
1.1 This practice describes the terms used in observing and recording cutaneous, gastrointestinal, respiratory, reproductive, neuromuscular, ocular, and general clinical signs of animals undergoing toxicological testing. This practice also assists in properly observing and assessing laboratory animals for signs of disease or adverse effects of compound administration.
1.2 This practice includes codes and descriptions for a wide variety of clinical signs, anatomical locations, and other descriptive qualifiers, and a technique for scoring the extent or severity of clinical signs.
1.3 This practice assumes that the reader is knowledgeable in animal toxicology and related pertinent areas and is trained in making clinical observations.
1.4 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.
PDF Catalog
PDF Pages | PDF Title |
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1 | Scope Referenced Documents Significance and Use Procedure General Clinical Signs |
2 | Specific Clinical Signs |
4 | Quality Assurance Keywords A1. CLINICAL SIGNS AND CODES A1.1 |
5 | TABLE A1.1 |
8 | A2. SEVERITY AND EXTENT SCALES A2.1 A3. ANATOMICAL LOCATIONS A3.1 TABLE A2.1 |
9 | TABLE A3.1 |